Quote from VidarThor »Preferably the turn after they play a creature, while they stil have one card in hand. Manadorks, goblin guide, taramagoyf, glistener elf. It really works quite well with all of them except lingering souls, kitchen finks and voice of resugerncy.
Inquesition can sett up a good play as well, and you get to know their hand.
Turn 1: Suspend Ancestral Vision, Inquesition or Fatal Push.
Turn 2: Brain in a Jar, Mycolot Wellspring, or smallpox if they have a creature.
As the game progresses you should be able to resolve an suspended ancestral vision, an acestral vision via yahennie's expertise, or one of the fuse cards off expertise or brain in the jar. From that point on you will likly be pulling away from the oponent through raw resources alone.
The way you describe smallpox, it seems like Fatal Push would just be better.